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White Cystalline Powder Pharma Raw Materials For Medicines Nateglinide 105816-04-4

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White Cystalline Powder Pharma Raw Materials For Medicines Nateglinide 105816-04-4

Brand Name : VANZ
Model Number : MEDICINE GRADE
Certification : COA
Place of Origin : CHINA(MAINLAND)
MOQ : 10g
Payment Terms : T/T, Western Union, MoneyGram
Supply Ability : customs-made
Delivery Time : 3days after paid
Packaging Details : in aluminium or on clients requirements
Appearance : white cystalline powder
purity : 99%
MF : C19H27NO3
MW : 317.4226
Melting point : 137-141°C
CAS NO. : 105816-04-4
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White Cystalline Powder Pharma Raw Materials For Medicines Nateglinide 105816-04-4


Introduction:

  • Nateglinide lowers blood glucose by stimulating the release of insulin from the pancreas. It achieves this by closing ATP-dependent potassium channels in the membrane of the β cells. This depolarizes the β cells and causes voltage-gated calcium channels to open. The resulting calcium influx induces fusion of insulin-containing vesicles with the cell membrane, and insulin secretion occurs.

Function:

  • It can be used for diet control and /or exercise therapy for unsatisfactory control of blood glucose levels of
  • type 2 diabets mellitus inpatients. It can be used as second-line drugs in treating typee 2 diabets mellitus inpatients with unsatisfactory control of blood glucose lecels as
  • sulfonylureas and metformin bydrochloride.


Specifications:


Product nameNateglinide
Density104 g/cm3
Boiling point527.6 °C at 760 mmHg
Flash point272.9 °C
chromato graphic purityComplyies
Identificationcomplies
Storagesealed save, cool ventilated dry place, prevent sun, rain.

ITEMSSPECIFICATIONSRESULTS
AppearanceWhite, crystalline powder or colorless crystalsPasses
IdentificationAccord With BP2007Passes
Assay98.5%~101.0%99.97%
Melting point75°C~78°C77°C
Optical rotation-0.05°~+0.05°0.00°
Heavy metals≤ 0.001%<0.001%
Related substances
Impurity B≤ 0.3%Passes
Any other impurity≤ 0.3%Passes
Total of all impurities apart from impurity B≤ 0.7%Passes
Impurity F≤ 0.1%Not detected
Sulphated ash≤ 0.1%0.02%
Appearance of solutionAccord With BP2007Passes
Conclusion: COMPLY WITH BP2007



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NOTES:


Those who are allergic to the chemicals, pregnant women, severe infection, severe trauma patients before and after surgery and diabetic coma and insulin-dependent diabetes patients disabled.


1. severe liver and kidney dysfunction, should be reduced or caution.


2. ischemic heart disease, pituitary and adrenal insufficiency deputy, diarrhea, vomiting and malnutrition in patients with caution.


3. Elderly patients and children with caution.


4. Use the regular testing of blood glucose, while other hypoglycemic drugs such as insulin sensitizers, α- glucosidase inhibitors in combination to adjust the dosage.


Packaging & Shipping:


1kg/Aluminum foil bag
1kg/ Aluminium Tin
25kg/Drum
25kg/ Aluminum Drum

Delivery Time:


Usually within 3 working days after confirming the payment.

Company's info




Product Tags:

Pharma Raw Materials

      

raw pharmaceutical materials

      
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